In Episode 39 of The Chris and Mike Show, the hosts delved into a comparison between Kamala Harris and Donald Trump. Mike praised the first 15 minutes of Trump's acceptance speech at the Republican National Convention, highlighting its strength before noting that it went sideways afterward. The discussion shifted to Joe Biden, with both hosts expressing a belief in his ineptitude, and they argued that Kamala Harris is unqualified to be president.

The episode also covered legal issues facing the NFL. The league is being sued by a Native American tribe whose chief was featured on the original logo, and another lawsuit has been filed by subscribers of the NFL Sunday Ticket. These subscribers claim the NFL violated antitrust laws by selling out-of-market Sunday afternoon game packages on CBS and Fox at inflated prices.

The remainder of the show included the hosts' typical banter, a guest appearance by Sgt. Jakob T. Dunham of the United States Marine Corps, and more of their usual conversations.